More News On Lymph Nodes and Breast Cancer Surgery

Last week the New England Journal of Medicine (NEJM) printed a major research article on lymph node dissection in breast cancer surgery. When I first saw the Times’ recent headline, I thought it would cover this paper: Effect of Occult Metastases on Survival in Node-Negative Breast Cancer.*

It turns out there were separate articles on axillary node dissection after sentinel node biopsy in breast cancer – one in JAMA and one in the NEJM – published a week apart. For some reason, the NEJM paper got little attention…

Posted in Breast Cancer, cancer treatment, Oncology (cancer), Pathology, Under the RadarTagged , , , , , , , , Leave a Comment on More News On Lymph Nodes and Breast Cancer Surgery

Breast Cancer Study Shows No Benefit In Extensive Lymph Node Removal

Today’s Times leads with a story on surgical removal of lymph nodes in women with breast cancer. The dramatic digital headline, Lymph Node Study Shakes Pillar of Breast Cancer Care, made me tremble at first glance. The article by Denise Grady covers a new report* in the Journal of the American Medical Association (JAMA).

The key finding is that for women with apparently limited disease before surgery who undergo subsequent radiation and chemotherapy, taking out all the cancerous nodes from the axilla (armpit) has no advantage.

I read the original publication and took some notes:

Posted in Breast Cancer, cancer treatment, Medical News, Oncology (cancer)Tagged , , , , , , Leave a Comment on Breast Cancer Study Shows No Benefit In Extensive Lymph Node Removal

Pink’s OK With Me

On Sunday, Feb. 20, the Northeastern Pennsylvania Affiliate of Susan G. Komen for the Cure will host its seventh annual Pink Elegance on Parade fashion show at the Radisson at Lackawanna Station hotel, reports the Scranton Times Tribune. The fundraiser will feature breast cancer survivors and others modeling fashions from Coldwater Creek, Lee’s Denim Diner, Luna Bleu and Suburban Casuals.

Some BC survivors, thrivors, thrivers, in-the-throws-ers and whatever we might call ourselves (I still can’t make up my mind on this) express disdain. Others, lately, convey cynicism, if not frank contempt, for the pink cancer culture in its entirety. Pink is tacky, pretty and possibly too rosy a color to link with the fate of so many sick and dying women.

I half-agree. But then again, I’ve never favored pastels:

Posted in Breast Cancer, cancer awareness, Essential Lessons, Oncology (cancer), Women's HealthTagged , , , , , 8 Comments on Pink’s OK With Me

After Breast Cancer, Get a Gym Membership!

The findings show that it’s safe for women who’ve had breast cancer surgery to work out in a way that includes a careful, progressive upper body strengthening. Weight lifting is not only safe; it can reduce lymphedema in women at risk. But “old wives’ tales” still persist in some doctors’ minds and established medical resources. These need be dispelled.

Posted in Breast Cancer, cancer survival, Essential Lessons, Fitness, Medical News, Oncology (cancer), Women's HealthTagged , , , , , , , , 1 Comment on After Breast Cancer, Get a Gym Membership!

Stem Cells, Breast Reconstruction and a Magazine Cover

The cover of the November print edition of Wired features large, unnatural-appearing cleavage. Inside and toward the back of the issue, a curious article ties together stem cells and the future of breast reconstruction. It got my attention. The detailed and admittedly interesting piece, by Sharon Begley, describes what’s science or science fiction: first humans, […]

Posted in Breast Cancer, cancer treatment, Future of Medicine, Magazine, Plastic and Reconstructive Surgery, ScienceTagged , , , , , , 1 Comment on Stem Cells, Breast Reconstruction and a Magazine Cover

New Findings on Postmenopausal Hormone Replacement Therapy and Breast Cancer

This week the Journal of the American Medical Association (JAMA) published results of a large study with significant implications for women who consider taking hormone replacement therapy (HRT). The new findings are based on careful examination over 16,000 individuals, part of the larger Women’s Health Initiative, who were randomly assigned to take either a placebo, […]

Posted in Breast Cancer, clinical trials, Oncology (cancer), Women's HealthTagged , , , , , , 1 Comment on New Findings on Postmenopausal Hormone Replacement Therapy and Breast Cancer

October 13 Would Be National Metastatic Breast Cancer Awareness Day

Last October, the U.S. Senate (on 10/13/09) and House (retroactively, on 10/28/09) voted to support the designation of October 13, 2009, as a National Metastatic Breast Cancer Awareness Day. The point was to draw public attention to the distinct needs of metastatic BC patients: women who live every day with this condition but, for the most part, are not heralded in pink.

Posted in Annals of Pink, Breast Cancer, cancer awareness, cancer survival, Oncology (cancer)Tagged , , , , , , Leave a Comment on October 13 Would Be National Metastatic Breast Cancer Awareness Day

Why I Went for My Screening Mammogram

I was afraid to get a mammogram because I didn’t want to learn I had cancer….I feared having a “false positive,” and undergoing multiple tests to evaluate abnormal images that would turn out to be nothing…I didn’t have time for all that…

Posted in Breast Cancer, cancer screening, Essential Lessons, Life as a Doctor, Life as a Patient, Oncology (cancer), Women's HealthTagged , , , , , , , , Leave a Comment on Why I Went for My Screening Mammogram

What’s Missing in the Recent Mammography Value Study

I’d say the oppo­site is true: It’s pre­cisely because there are effec­tive treat­ments for early-stage dis­ease that it’s worth find­ing breast can­cer early. Oth­er­wise, what would be the point?

Metasta­tic breast can­cer is quite costly to treat and, even with some avail­able tar­geted ther­a­pies, remains

Posted in Breast Cancer, cancer awareness, cancer screening, cancer survival, Diagnosis, Medical News, Oncology (cancer)Tagged , , , , , , Leave a Comment on What’s Missing in the Recent Mammography Value Study

Stepping Back, and Thinking Forward to October

A question central to today’s discussion – which does at least acknowledge the decline in breast cancer mortality – is the extent to which mammography is responsible for this trend, as opposed to other factors such as increased awareness about cancer, better cancer treatments and other variables.

Posted in Breast Cancer, cancer awareness, cancer screening, clinical trials, health care costs, Medical News, Oncology (cancer)Tagged , , , , Leave a Comment on Stepping Back, and Thinking Forward to October

A Walk, or Race, for the Cure

“You can get discomboobulated in this place,” a NYC police officer told me today.

This morning, some 25,000 or so men, women and children converged on Central Park for the Susan G. Komen Foundation’s 20th annual Race for the Cure. It was my first time witnessing the event:

Posted in Annals of Pink, Breast Cancer, cancer awareness, cancer survival, Life as a Patient, Life in NYCTagged , , , , , , 2 Comments on A Walk, or Race, for the Cure

New NY State Law on Information for Women Undergoing Mastectomy

The reality is that many women, particularly poor women without newspapers or internet access in their homes, don’t know about any of this. They don’t know their insurance covers pretty much all of these options, by law. Now they will, or should as of Jan 1, 2011. Good. The other curiosity is that …

Posted in Breast Cancer, cancer treatment, Communication, Medical News, Patient Autonomy, Plastic and Reconstructive SurgeryTagged , , , , , , , 2 Comments on New NY State Law on Information for Women Undergoing Mastectomy

The “Survivor” Term After Breast Cancer: Is There a Better Expression?

The question is, what’s the right, PC and emotionally-sound, sensitive but not sappy term to describe the situation of a person who’s living after breast cancer?

Some might say, who cares if you’ve had it?

Posted in Breast Cancer, cancer awareness, cancer survival, Essential Lessons, language, Oncology (cancer), Psychiatry, Women's HealthTagged , , , , , , 35 Comments on The “Survivor” Term After Breast Cancer: Is There a Better Expression?

Suggestions to Reduce Errors in Breast Cancer Pathology

A prominent article in yesterday’s New York Times considers some troubling problems regarding inaccuracy in breast cancer diagnosis and pathology. The main point is that some women get needless, disfiguring and toxic treatments after being told they have breast cancer when, it turns out, their condition was benign. My main take is that, whenever possible, […]

Posted in Breast Cancer, Diagnosis, Oncology (cancer), Pathology, Women's HealthTagged , , , , , , 1 Comment on Suggestions to Reduce Errors in Breast Cancer Pathology

Mind over Matter? Don’t Kid Yourself (on Stress and BC)

I learned of a new study implicating stress in reduced breast cancer survival by Twitter. A line in my feed alerted me that CNN’s health blog, “Paging Dr. Gupta,” broke embargo on the soon-to-be-published paper in the journal Clinical Cancer Research. The story – that women who undergo a stress relief program live longer after […]

Posted in Breast Cancer, cancer survival, clinical trials, Essential Lessons, Medical News, Oncology (cancer), Pseudoscience, Psychiatry, Women's HealthTagged , , , , , , , , , 3 Comments on Mind over Matter? Don’t Kid Yourself (on Stress and BC)

Why Blog on OncotypeDx and BC Pathology?

I can’t even begin to think of how much money this might save, besides sparing so many women from the messy business of infusions, temporary or semi-permanent IV catheters, prophylactic or sometimes urgent antibiotics, Neulasta injections, anti-nausea drugs, cardiac tests and then some occasional deaths in treatment from infection, bleeding or, later on, from late effects on the heart or not-so-rare secondary malignancies like leukemia. And hairpieces; we could see a dramatic decline in women with scarves and wigs.

Posted in Breast Cancer, cancer treatment, Communication, Diagnosis, Empowered Patient, health care costs, Informed Consent, Pathology, Patient AutonomyTagged , , , , , , , , 2 Comments on Why Blog on OncotypeDx and BC Pathology?

More News, and Considerations, on OncotypeDx

This week I’ve been reading about new developments in breast cancer (BC) pathology. At one level, progress is remarkable. In the 20 years since I began my oncology fellowship, BC science has advanced to the point that doctors can distinguish among cancer subtypes and, in principle, stratify cases according to patterns of genes expressed within […]

Posted in Breast Cancer, cancer treatment, clinical trials, Diagnosis, Informed Consent, Oncology (cancer), Pathology, Patient AutonomyTagged , , , , , , , , , Leave a Comment on More News, and Considerations, on OncotypeDx

Another Erroneous Report on Breast Cancer Screening by Mammography

What the authors tried to do was analyze trends in breast cancer mortality in relation to mammography’s availability in distinct regions of Denmark over several decades. Using Poisson regression, a form of statistical analysis, they looked for a correlation and found none. They concluded that they couldn’t detect a benefit of screening mammograms among Danish women who might benefit (see below).

Here’s what I think are the two most serious flaws in this observational study:

Posted in Breast Cancer, cancer screening, Under the RadarTagged , , , , Leave a Comment on Another Erroneous Report on Breast Cancer Screening by Mammography

A Small Study Offers Insight On Breast Cancer Patients’ Capacity and Eagerness to Participate in Medical Decisions

Last week the journal Cancer published a small but noteworthy report on women’s experiences with a relatively new breast cancer decision tool called Oncotype DX. This lab-based technology, which has not received FDA approval, takes a piece of a woman’s tumor and, by measuring expression of 21 genes within, estimates the likelihood, or risk, that her tumor will recur.

As things stand, women who receive a breast cancer diagnosis face difficult decisions…

Posted in Breast Cancer, cancer survival, Communication, Diagnosis, Empowered Patient, Informed Consent, Oncology (cancer), Pathology, Patient Autonomy, Patient-Doctor Relationship, Statistics, Under the RadarTagged , , , , , , , , , , 5 Comments on A Small Study Offers Insight On Breast Cancer Patients’ Capacity and Eagerness to Participate in Medical Decisions

New Boss on The Office is a Breast Cancer Survivor

There’s a new survivor on TV and she means business.

In the latest episode of The Office, Kathy Bates walked into the Scranton branch of Dundler Mifflen and onto my living room TV screen as Jo Bennett, CEO of Sabre, a fictitious Tallahassee-based company. An assistant and two large canines accompany her as she meets the crew. She’s firm, graying and very much-in-charge.

When the camera gets her alone, in focus, here’s what she has to say:

“I’m Jolene Bennett, Jo for short.

“I’m a breast cancer survivor, close personal friends with Nancy Pelosi, and Truman Capote and I slept with three of the same guys. When I was a little girl I was terrified to fly, and now I have my own pilot’s license.

“I am CEO of Sabre International and I sell the best damn printers and all-in-one machines Korea can make.

“Pleased to meet ya.

Posted in Breast Cancer, cancer survival, Reviews, TVTagged , , , , , , , , , 1 Comment on New Boss on The Office is a Breast Cancer Survivor
newsletter software